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. 2018 Dec 5;147:e66. doi: 10.1017/S0950268818003096

Table 3.

The number and percent of observational studies that examine animal hosts for natural exposure to and/or infection with La Crosse virus (LACV) in the literature (N = 31)

Overall LACV Positive
Animal category Species* N % N
Wild animals
Deer White-tailed deer (Odocoileus virginianus)a 9 29.0 7
Mule deer (Odocoileus hemionus) 2 6.5 2
Elk Cervus elaphus 1 3.2 0
Moose Alces alces 1 3.2 0
Fox Red fox (Vulpes fulva)a 2 6.5 1
Grey fox (Urocyon cinereoargenteus) 1 3.2 1
Slothb Two-toed sloths (Choloepus hoffmanni) 1 3.2 0
Three-toed sloths (Bradypus variegatus) 1 3.2 0
Raccoon Procyon lotorc 4 12.9 3
Opossum Didelphis virginianusc 2 6.5 0
Didelphis marsupialis 1 3.2 0
Bird Ruffed grouse (Bonasa umbellus) 1 3.2 0
Mute swans (Cygnus olor) 1 3.2 0
Rabbitsb Eastern cottontail rabbits (Sylvilagus floridanus)a 3 9.7 1
Species not reported 3 9.7 1
Rodents
Squirrels Gray squirrels (Sciuris carolinensis)a 5 16.1 4
Fox squirrel (S. niger)a 1 3.2 1
Species not reported 1 3.2 1
Chipmunks Eastern chipmunks (Tamias striatus)a 11 35.5 9
Species not reported 1 3.2 1
Woodchuck/groundhog Marmota monaxa 1 3.2 1
Rat Rattus spp. 1 3.2 0
Muskrat Ondatra zibethicus 1 3.2 0
Domestic/farm animals
Cat Felis catusc 1 3.2 0
Dog Canis familiarisc,d 3 9.7 3
Pig Sus domesticusc 1 3.2 1
Sheep Ovis ariesc 1 3.2 0
Goat Capra hircusc 2 6.5 0
Horse Equus caballusc 2 6.5 2
Cattle Bos taurusc 1 3.2 1

N/A, Not applicable as the study did not report any LACV positive samples.

a

Species indicated by the author to be part of the sylvatic cycle.

b

All samples were collected from the USA except for one study that sampled rabbits from Canada and one study that sampled sloths from Costa Rica, both did not find evidence of LACV exposure.

c

Species indicated by the author to be dead-end host.

d

Species indicated by the author to suffer from clinical LACV infection.

*All animals were tested for LACV using antigen-antibody assays. Three studies used viral isolation methods to detect LACV in gray squirrels (S. carolinensis) and eastern chipmunks (T. striatus) (S4).