Table 4.
The number and percent of articles examining experimental animal models of La Crosse virus (LACV) infection across different study foci (N = 78)
| Animal model category | Study focus* | N | % |
|---|---|---|---|
| Mice (n = 64) | Pathogenesis | 29 | 37.2 |
| Treatment efficacy | 2 | 2.6 | |
| Diagnostic accuracy | 2 | 2.6 | |
| Transmission | 34 | 43.6 | |
| Mitigation | 5 | 6.4 | |
| Monkeys (n = 2) | Pathogenesis | 1 | 1.3 |
| Mitigation | 1 | 1.3 | |
| Chipmunks (n = 12) | Pathogenesis | 8 | 10.3 |
| Diagnostic accuracy | 1 | 1.3 | |
| Transmission | 9 | 11.5 | |
| Squirrels (n = 2) | Pathogenesis | 2 | 2.6 |
| Diagnostic accuracy | 1 | 1.3 | |
| Transmission | 1 | 1.3 | |
| Deer (n = 3) | Pathogenesis | 2 | 2.6 |
| Transmission | 2 | 2.6 | |
| Gerbils/guinea pigs/hamsters (n = 10) | Pathogenesis | 4 | 5.1 |
| Diagnostic accuracy | 2 | 2.6 | |
| Transmission | 7 | 9.0 | |
| Rabbits (n = 3) | Pathogenesis | 2 | 2.6 |
| Transmission | 2 | 2.6 | |
| Foxes (n = 1) | Pathogenesis | 1 | 1.3 |
| Transmission | 1 | 1.3 | |
| Raccoon (n = 1) | Pathogenesis | 1 | 1.3 |
| Transmission | 1 | 1.3 | |
| Opossum (n = 1) | Pathogenesis | 1 | 1.3 |
| Transmission | 1 | 1.3 | |
| Sheep (n = 1) | Pathogenesis | 1 | 1.3 |
*Total may not add to 100% as a single study may contain results for more than one species and several focus areas.