Table 3.
Mean Ct value, Sensitivity, Specificity, PPV, and NPV of mSEPT9 and FOBT in the CRC group and adenoma and polyps’ group
| CRC | Adenoma and Polyps | |||
|---|---|---|---|---|
| mSEPT9 | FOBT | mSEPT9 | FOBT | |
| Mean Ct value | 39.24 | 42.65 | ||
| Sensitivity | 73.0% (60.1%~ 83.1%) |
58.7% (45.6–70.8%) |
17.1% (10.0–27.3%) |
12.2% (6.3–21.7%) |
| Specificity | 94.5% (92.0%~ 96.3%) |
91.9% (89.0–94.1%) |
94.5% (92.0%~ 96.3%) |
91.9% (89.0–94.1%) |
| PPV | 63.0% (50.9%~ 73.8%) |
48.1% (36.6–59.7%) |
34.1% (20.6%~ 50.7%) |
20.0% (10.5–34.1%) |
| NPV | 96.5% (94.3%~ 97.9%) |
94.6% (92.1–96.4%) |
87.3% (84.1%~ 89.9%) |
86.3% (83.0–89.1%) |