Table 8.
Correlation of clinical parameters and mSEPT9 with Dukes stages
| Clinicopathological parameters | Dukes A(n) | Dukes B(n) | Dukes C(n) | Dukes D(n) | P | OR (95%CI) |
|---|---|---|---|---|---|---|
| Gender | 0.973 | 0.58(−3.669–6.557) | ||||
| Female | 1 | 10 | 10 | 4 | ||
| Male | 2 | 14 | 12 | 4 | ||
| Age | 0.744 | 0.459(−10.312–4.655) | ||||
| ≤ 60 | 0 | 9 | 9 | 3 | ||
| > 60 | 3 | 15 | 13 | 5 | ||
| Localization | 0.405 | 0.338(−2.644–7.702) | ||||
| Colon and Rectosigmoid transition | 2 | 10 | 10 | 6 | ||
| Rectum | 1 | 14 | 12 | 2 | ||
| Depth of invasion | 0 | 0.104(−1.47–15.66) | ||||
| T1 + T2 | 3 | 0 | 2 | 0 | ||
| T3 | 0 | 20 | 14 | 1 | ||
| T4 | 0 | 4 | 6 | 7 | ||
| Lymphatic metastasis (N) | 0 | 0.042(0.744–39.596) | ||||
| Nx + N0 | 3 | 24 | 1 | 0 | ||
| N1 + N2 | 0 | 0 | 21 | 8 | ||
| Distant metastasis (M) | 0 | 0.166(−8.463–49.171) | ||||
| Mx + M0 | 3 | 24 | 22 | 0 | ||
| M1 | 0 | 0 | 0 | 8 | ||
| Tumor differentiation | 0.026 | 0.21(−16.733–3.676) | ||||
| Well and moderately differentiated | 3 | 18 | 11 | 2 | ||
| Poorly differentiated | 0 | 6 | 11 | 6 | ||
| Gross tumor volume | 0.282 | 0.69(−11.985–7.936) | ||||
| 0–10 cm3 | 2 | 6 | 10 | 2 | ||
| > 10 cm3 | 1 | 18 | 12 | 6 | ||
| mSEPT9 | 0.026 | 0.766(−13.507–9.948) | ||||
| Positive | 1 | 22 | 14 | 7 | ||
| Negative | 2 | 2 | 8 | 1 |