Fig. 1.

Regrouping and matching of samples. One H24 sample from a survivor was excluded due to the problem of NMR gain parameter; one H0 sample from a non-survivor was excluded as it was found to be an outlier in PCA. For the paired H0-H24 samples obtained from the same patients, the pairs have been divided into training set and test set. The pairs of survivors and non-survivors were analyzed separately. Samples in the training set were analyzed for establishing discriminatory models between H0 and H24 samples. The pairs in the test set were reanalyzed in the established models