Table 1.
Baseline characteristics of the patients recorded at admission to the ICU
| Total/average | Survivors | Non-survivors | Adj P | FDR | |
|---|---|---|---|---|---|
| Number of patients | 70 | 40 | 30 | ||
| Male (%) | 40 (57%) | 27 (67%) | 13 (32%) | 0.07 | 0.09 |
| Age | 70.1 ± 0.16 | 68.5 ± 0.29 | 72.1 ± 0.36 | 0.12 | 0.23 |
| Temperature (°C) | 37.3 ± 0.02 | 37.1 ± 0.03 | 36.9 ± 0.05 | 0.32 | 0.35 |
| Mean arterial pressure (mmHg) at admission | 72.8 ± 2,44 | 71,0 ± 3,25 | 75.2 ± 3.72 | 0.41 | 0.35 |
| pH at admission | 7.3 ± 0.00 | 7.31 ± 0.00 | 7.29 ± 0.00 | 0.43 | 0.53 |
| PaO2 (mmHg)H0 | 144.7 ± 1.54 | 167.5 ± 2.83 | 113.6 ± 3.12 | 0.05 | 0.13 |
| PaCO2 (mmHg) | 37.6 ± 0.18 | 37.6 ± 0.31 | 37.5 ± 0.45 | 0.66 | 0.63 |
| PaO2/FiO2 ratioH0 | 212.5 ± 4.10 | 168.6 ± 3.19 | 242.2 ± 5.59 | 0.04 | 0.07 |
| Lactate (mmol/L)H0 | 5.0 ± 0.07 | 3.7 ± 0.11 | 6.6 ± 0.17 | 0.01 | 0.03 |
| Creatininemia (μmol/L)H0 | 212.2 ± 3.88 | 200.1 ± 4.34 | 241.9 ± 3.55 | 0.07 | 0.15 |
| Glycemia (mmol/L) | 9.8 ± 0.09 | 9.9 ± 0.20 | 9.6 ± 0.23 | 0.91 | 0.95 |
| Hemoglobin (mmol/L) | 10.5 ± 0.03 | 10.1 ± 0.06 | 10.9 ± 0.07 | 0.09 | 0.06 |
| Albumin (g/L) | 24.6 ± 0.13 | 22.2 ± 0.15 | 26.8 ± 0.38 | 0.11 | 0.21 |
| Platelet (g/L) | 156.7 ± 1.53 | 151.8 ± 2.61 | 162.2 ± 3.70 | 0.33 | 0.13 |
| Total bilirubin (μmol/L) | 38.4 ± 0.90 | 37.8 ± 1.90 | 39.1 ± 1.53 | 0.54 | 0.77 |
| CRP (mg/dL) | 162.3 ± 2.15 | 174.0 ± 3.98 | 147.4 ± 4.71 | 0.49 | 0.67 |
| PCT (mg/dL) | 25.2 ± 0.52 | 28.0 ± 1.15 | 21.6 ± 1.39 | 0.74 | 0.88 |
| SAPSII | 59.0 ± 0.24 | 55.2 ± 0.39 | 64.3 ± 0.58 | 0.02 | 0.07 |
| SOFAH0 | 11.7 ± 0.06 | 10.9 ± 0.11 | 12.4 ± 0.12 | 0.10 | 0.15 |
| SOFAH24 | 9.4 ± 0.06 | 8.7 ± 0.11 | 10.3 ± 0.10 | 0.07 | 0.11 |
| ICU LOS (day) | 9.16 ± 1.21 | 15.1 ± 1.36 | 3.62 ± 0.09 | 0.05 | 0.09 |
| Mechanical ventilation (%) | 84% | 75% | 93% | ||
| Hospital-acquired infection (%) | 45% | 35% | 60% | ||
| Sepsis causes (%) | |||||
| Pulmonary | 54% | 55% | 53% | ||
| Abdominal | 30% | 22% | 40% | ||
| Urinary tract | 7% | 7% | 6% | ||
| Others | 8% | 15% | 0% | ||
All the data is represented as mean ± standard error of mean (SEM)
PaO2 partial pressure of arterial oxygen, FiO2 percentage of inspired oxygen, SOFA Sepsis-related Organ Failure Assessment, SOFAH0 SOFA measured at H0, SOFAH24 SOFA measured at H24, SAPSII new simplified acute physiology score, LOS length of stay, FDR false discovery rate, Adj P P value adjusted with Bonferroni correction