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Effect of G2-S16 on the activation state of T-cells. Non- and PHA-activated PBMCs were treated with G2-S16 (10 µM) for 48 h and protein expression was determined by flow cytometry. We studied the activation markers for early activation, CD69 (a, b) and late activation HLA-DR (c, d). For each marker, the percentage of positive cells (a, c) and the mean fluorescence intensity (b, d) were analyzed
