Table 4.
List of most significant enriched biological themes and functional-related gene groups identified by DAVID (http://david.abcc.ncifcrf.gov) among the top 43 mutated genes with > 10 mutations in 66 PDAC tumors from The Cancer Genome Atlas database (TGCA, provisional, accessed January 17, 2014). The top terms included “SM00112:CA cadherin repeats (SMART)”, “IPR0020894:Cadherin conserved site” (INTERPRO), “IPR002126:Cadherin” (INTERPRO), “domain:Cadherin 5” (UP SEQ FEATURE). The table is ordered according to Bonferroni correction and all included terms were statistically significant after Bonferroni and Benjamini corrections. Protocadherin genes recurring in the table are in bold