Table 2.
Cox-model-measured hazard ratios and 95% confidence intervals of chronic fatigue syndrome associated with psoriasis and covariates
| Variable | Event no. | Person-years | IR | HR (95% CI) | |
|---|---|---|---|---|---|
| Univariate | Multivariatea | ||||
| Psoriasis | |||||
| No | 126 | 55,446 | 2.27 | 1.00 | 1.00 |
| Yes | 50 | 13,958 | 3.58 | 1.58 (1.14–2.19)** | 1.48 (1.07–2.06)* |
| Sex | |||||
| Women | 91 | 32,509 | 2.80 | 1.00 | 1.00 |
| Men | 85 | 36,895 | 2.30 | 0.82 (0.61–1.11) | 0.86 (0.64–1.17) |
| Age, years | |||||
| 20–39 | 62 | 31,599 | 1.96 | 1.00 | 1.00 |
| 40–59 | 60 | 23,974 | 2.50 | 1.28 (0.90–1.82) | 1.17 (0.81–1.68) |
| ≥ 60 | 54 | 13,832 | 3.90 | 1.99 (1.38–2.87)*** | 1.64 (1.10–2.45)* |
| Comorbidity | |||||
| Diabetes | |||||
| No | 158 | 63,598 | 2.48 | 1.00 | 1.00 |
| Yes | 18 | 5806 | 3.10 | 1.25 (0.77–2.03) | 0.83 (0.49–1.38) |
| Depression | |||||
| No | 158 | 66,645 | 2.37 | 1.00 | 1.00 |
| Yes | 18 | 2760 | 6.52 | 2.75 (1.69–4.48)*** | 1.51 (0.89–2.57) |
| Anxiety | |||||
| No | 153 | 65,385 | 2.34 | 1.00 | 1.00 |
| Yes | 23 | 4020 | 5.72 | 2.44 (1.58–3.79)*** | 1.30 (0.80–2.11) |
| Sleep disorder | |||||
| No | 115 | 58,403 | 1.97 | 1.00 | 1.00 |
| Yes | 61 | 11,002 | 5.54 | 2.81 (2.06–3.84)*** | 2.17 (1.53–3.08)*** |
| Renal disease | |||||
| No | 161 | 66,170 | 2.43 | 1.00 | 1.00 |
| Yes | 15 | 3234 | 4.64 | 1.91 (1.13–3.24)* | 1.26 (0.73–2.20) |
IR incidence density rate per 1000 person-years, HR hazard ratio, CI confidence interval
* P < 0.05, ** P < 0.01, *** P < 0.001
aAdjusted for psoriasis, sex, age (categorical), diabetes, depression, anxiety, sleep disorder, and renal disease