Table 3.

Predictive performance of the three models

	Training cohort				Validation cohort
	AUC(95%CI)	SEN	SPE	P	AUC(95%CI)	SEN	SPE	P
(1) Radiomics score	0.757 (0.667–0.846)	92.3	44.6		0.728 (0.580–0.877)	69.6	70.8
(2) Clinical-radiological nomogram	0.796 (0.712–0.881)	75.0	76.8		0.814 (0.682–0.947)	78.3	83.3
(3) Radiomics nomogram	0.844 (0.769–0.919)	73.1	85.7		0.841 (0.722–0.959)	91.3	75.0
1 vs. 2				0.453				0.310
1 vs. 3				0.012*				0.013*
2 vs. 3				0.045*				0.131

1 indicates radiomics score; 2 indicates clinical-radiological nomogram; 3 indicates radiomics nomogram

SEN sensitivity, SPE specificity, AUC area under the curve, CI confidence interval

*P < 0.05 indicates a significant difference