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. 2019 May 14;38:194. doi: 10.1186/s13046-019-1188-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The prognostic value of AGAP2-AS1 and miR-16-5p for HCC patients. a and (b) Overall survival and disease-free survival were compared between AGAP2-AS1 high expressing HCC patients and low expressing cases. c and (d) Overall survival and (d) disease-free survival were compared between miR-16-5p high expressing HCC patients and low expressing cases. e and (f) Overall survival and disease-free survival were compared between four subgroups of HCC patients. For each cohort, subgroups were divided according to the cutoff values of AGAP2-AS1 and miR-16-5p. The cutoff value was determined as the median value of the relative expression of AGAP2-AS1 and miR-16-5p in HCC tissues. **P < 0.01