Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 5;37(4):855–866. doi: 10.1002/jor.24245

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of the Orthopaedic Research Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Representative CEμCT slice and corresponding histology from osteochondral plugs with different OA degeneration stages a) Smooth and continuous AC surface with no distinguishable features in parameter maps or 3D surface. b) Discontinuities in AC surface with a cavern‐like structure in the tortuosity map and discernable patterns in a Maximum Void Depth (MVD) map and 3D surface. c) Fibrillation with distinct changes in both MVD and Tortuosity; more areas with surface complexity can be seen on the 3D surface. d) Severe degeneration can be seen in the MVD and tortuosity maps as well as on the 3D surface with very complex defects penetrating to deep AC.