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. 2019 Jul-Sep;6(3):253–260. doi: 10.4103/apjon.apjon_7_19

Table 3.

Multivariate associations of neuropathy and demographic and cancer-related factors with any functional impairment in cancer patients with chemotherapy-induced peripheral neuropathy

Predictor Estimated adjusted OR

OR 95% CI P
Age: ≥65 vs. <65 yearsa 1.108 0.248 4.948 0.893
Educational level: ≤ high school vs. ≥college 0.213 0.053 0.858 0.030
Employment: Unemployed vs. employed 0.466 0.133 1.639 0.234
Metastasis: Yes vs. no 0.319 0.018 5.784 0.440
Total dose of taxane anticancer agents 1.000 1.000 1.001 0.211
NCI-CTCAE version 4.0 grade: ≥2 vs. 1 6.415 1.271 32.379 0.024
Total score of FACT/GOG-NTX 0.874 0.808 0.946 0.001

a≥65 years=0, <65 years=1. NCI-CTCAE: National Cancer Institute Common Terminology Criteria for Adverse Events, FACT/GOG-NTX: Functional Assessment of Cancer Therapy-Gynecologic Oncology Group-Neurotoxicity, OR: Odds ratio, CI: Confidence interval