Table 2.

Cox’s proportional hazards regression model of overall survival for the 419 patients with nasopharyngeal carcinoma in training set

Variable	Univariate analysis		Multivariate analysis
HR (95% CI)	P	HR (95% CI)	P
Age (years)
≥45 vs <45	2.656 (1.101–6.404)	0.030	2.454 (1.002–6.007)	0.049
Stage
T2N0	1	0.043
T1N1 vs T2N0	4.865 (0.621–38.109)	0.132
T2N1 vs T2N0	9.650 (1.253–74.315)	0.030
N category
N1 vs N0	3.318 (1.940–5.677)	0.035
Lymph node site
Site 1	1	0.013
Site 2 vs Site 1	4.455 (0.534–37.157)	0.167
Site 3 vs Site 1	11.586 (1.541–87.111)	0.017
NLR group
≥2.80 vs <2.80	3.254 (1.421–7.451)	0.005	2.425 (1.024–5.739)	0.044
Fibrinogen (mg/mL)
≥3.30 vs <3.30	1.151 (1.008–1.314)	0.038
EBV DNA (copies/mL)
≥3000 vs <3000	2.896 (1.238–6.774)	0.014	2.434 (1.009–5.871)	0.048
Therapy
RT vs CCRT	3.315 (1.487–7.388)	0.003	2.716 (1.168–6.317)	0.020

Notes: Lymph node site: lymph node location. Site 1= retropharyngeal lymph node, Site 2= unilateral cervical lymph node, Site 3= retropharyngeal and unilateral cervical lymph nodes.

Abbreviations: HR, hazard ratio; CI, confidence interval; NLR, Neutrophil/Lymphocyte Ratio; RT, Radiotherapy; CCRT, Concurrent chemoradiotherapy.