Table 1.
Patient demographics and mean and SD of pulmonary function tests and quantitative CT data
| Variable (n = 152 unless stated) Units are percentage unless stated |
Value |
|---|---|
| Median age (years, range) | 67 (38–86) |
| Male/female | 122/30 |
| Never/ever/current smokers | 50/100/2 |
| Alive/dead | 51/101 |
| GAP index (1/2/3) (n = 136) | 44/73/19 |
| FEV1% predicted (n = 138) | 73.7 ± 19.4 |
| FVC % predicted (n = 138) | 72.7 ± 20.7 |
| DLCO % predicted (n = 141) | 38.9 ± 12.9 |
| KCO % predicted (n = 141) | 69.9 ± 19.0 |
| TLC % predicted (n = 132) | 67.2 ± 16.5 |
| CPI (n = 137) | 52.2 ± 11.8 |
| Computed metrics | |
| Total lung volume (L) | 3.9 ± 1.1 |
| Normalized vessel volume (%) | 3.6 ± 0.8 |
| Normalized arterial volume (%;n = 106) | 2.1 ± 0.5 |
| Normalized venous volume (%; n = 106) | 1.6 ± 0.4 |
| Vessel density (vess/L) | 361.5 ± 106.1 |
| Arterial density (vess/L; n = 106) | 198.9 ± 53.9 |
| Venous density (vess/L; n = 106) | 167.6 ± 48.7 |
| Vessel tortuosity (1) | 1.029 ± 0.003 |
| Arterial tortuosity (1; n = 106) | 1.029 ± 0.004 |
| Venous tortuosity (1; n = 106) | 1.029 ± 0.003 |
| Vessel heterogeneity (1) | 0.058 ± 0.006 |
| Arterial heterogeneity (1; n = 106) | 0.057 ± 0.007 |
| Venous heterogeneity (1; n = 106) | 0.058 ± 0.006 |
CPI, composite physiologic index; CT, computed tomography; DLCO, diffusion capacity for carbon monoxide; FEV1, forced expiratory volume in the first second; FVC, forced vital capacity; GAP, gender age physiology; KCO, transfer factor for carbon monoxide; TLC, total lung capacity.