Table 2.

Concordance results for anxiety disorders or PTSD and subcortical volume overlap (P-value, CI, direction of effect).

Brain volume	Anxiety disorder, Factor score	Anxiety disorder, Case-control	PTSD
Intracranial volume	1 (1–1), +	0.257 (0.249–0.266), −	0.0852 (0.0799–0.0908), −
Accumbens	0.164 (0.156–0.171), −	0.0023 (1.53×10−3–3.45×10−3)**, −	1 (1–1), −
Amygdala	0.0001 (5.13×10−6–5.66×10−4)***, −	0.0001 (5.13×10−6–5.66×10−4)***, −	0.0162 (0.0139–0.0189)**, −
Caudate	1 (1–1), +	0.139 (0.132–0.146), −	0.0555 (0.0512–0.0602), +
Hippocampus	1 (1–1), −	0.109 (0.103–0.116), −	0.0479 (0.0439–0.0523)**, −
Pallidum	0.107 (0.102–0.114), +	1 (1–1), −	0.1730 (0.166–0.181), −
Putamen	0.0079 (6.34×10−3–9.83×10−3)**, −	0.218 (0.21–0.227), −	0.2160 (0.208–0.224), +
Thalamus	0.213 (0.205–0.221), +	0.249 (0.241–0.258), +	0.0101 (0.00832–0.0123)**, −

Bonferroni corrected p-value at 0.05/32 = 0.00156.

^**Marginal significance (p<0.05)

^***Significant (p<0.00156)