Table 4. Significant variants associated with PTSD risk when conditioning on brain volume GWAS.

The chromosome (Chr) and base pair (BP) are given in h19b37 coordinates. The Effect in Brain and Effect in post traumatic stress disorder (PTSD) are both given in terms of the effect allele (EA). The non-effect allele (NEA) is also shown. The allele frequency (Freq) corresponds to the effect allele. Tagging SNP corresponds to the most significant variant in a given LD block (if different from the SNP chosen based on clumping in the brain volume GWAS).

Brain volume	SNP	Chr	BP	EA	NEA	Freq	Nearest Gene	Distance to Gene	Effect in Brain (SE)	P-value in Brain	Effect in PTSD (SE)	P-value in PTSD	q-value
Putamen	rs6470292	8	125868043	A	G	0.8155	MIR4662B	33kb	−36.2473 (7.71)	2.55×10−6	−0.485 (0.048)	0.00184	0.0476
	rs683250	11	83276168	A	G	0.625	DLG2	Intronic variant	−33.965 (6.08)	2.33×10−8	−0.114 (0.039)	0.003528	0.0476