Table 1.
Comparison of characteristics between women with and without PE
| Basic demographics | Women with PE | Women without PE | Univariate odds ratio (95% CI) | Univariate P‐Value | Multivariate odds ratio (95% CI) | Multivariate P‐value |
|---|---|---|---|---|---|---|
| Age over 35 years | 37 (20.44%) | 40 (15.44%) | 1.41 (0.86–2.31) | 0.176 | – | – |
| Age (continuous) | – | – | 1.02 (0.99–1.05) | 0.179 | 1.06 (1.01–1.11) | 0.026 |
| BMI 30 or more | 60 (33.15%) | 85 (32.82%) | 1.01 (0.68–1.52) | 0.942 | – | – |
| BMI (Continuous) | – | – | 1.01 (0.99–1.04) | 0.372 | 1.03 (0.99–1.07) | 0.153 |
| Smoking Status | ||||||
| Never | 116 (64.09%) | 171 (66.02%) | Reference | – | – | |
| Gave up before | 28 (15.47%) | 39 (15.06%) | 1.06 (0.61–1.81) | 0.837 | 1.09 (0.49–2.41) | 0.828 |
| Gave up during | 23 (12.71%) | 19 (7.34%) | 1.78 (0.93–3.46) | 0.082 | 2.35 (0.93–5.92) | 0.070 |
| Current | 14 (7.73%) | 30 (11.58%) | 0.69 (0.34–1.33) | 0.279 | 1.17 (0.44–3.10) | 0.755 |
| Previous pregnancies | ||||||
| ≥1 previous pregnancy <24 weeks | 68 (37.57%) | 97 (37.45%) | 1.00 (0.68–1.49) | 0.98 | – | – |
| N of previous pregnancies <24 weeks (Continuous) | – | – | 1.05 (0.91–1.23) | 0.509 | 0.96 (0.79–1.18) | 0.713 |
| ≥1 previous pregnancy >24 weeks | 126 (69.61%) | 165 (63.71%) | 1.30 (0.87–1.97) | 0.198 | – | – |
| N of previous pregnancies >24 weeks (Continuous) | – | – | 1.20 (1.04–1.30) | 0.017 | 0.94 (0.72–1.22) | 0.636 |
| Previous Pregnancy Problems | 55 (30.39%) | 70 (27.03%) | 1.18 (0.77–1.79) | 0.442 | 1.17 (0.60–2.26) | 0.646 |
| Previous medical problems | ||||||
| Family history of thrombosis | 24 (13.26%) | 46 (17.76%) | 0.71 (0.41–1.20) | 0.205 | 0.35 (0.14–0.90) | 0.029 |
| History of varicose veins | 5 (2.76%) | 19 (7.34%) | 0.36 (0.12–0.91) | 0.045 | 0.42 (0.09–1.86) | 0.251 |
| History of IV drug use | 1 (0.55%) | 1 (0.39%) | 1.43 (0.06–36.4) | 0.8 | 0 | 1.0 |
| Known thrombophilia | 4 (2.21%) | 7 (2.70%) | 0.81 (0.21–2.74) | 0.745 | 0.12 (0.01–1.26) | 0.077 |
| Surgery in previous 4 weeks | 35 (19.34%) | 21 (8.11%) | 2.72 (1.53–4.92) | 0.001 | 0.85 (0.30–2.40) | 0.753 |
| Significant injury in the previous 4 weeks | 2 (1.10%) | 3 (1.16%) | 0.95 (0.12–5.81) | 0.959 | 0.42 (0.03–5.45) | 0.505 |
| History of thrombosis | 19 (10.50%) | 15 (5.79%) | 1.91 (0.95–3.92) | 0.073 | 3.07 (1.05–8.99) | 0.041 |
| Other previous medical problem | 75 (41.44%) | 110 (42.47%) | 0.96 (0.65–1.41) | 0.829 | – | – |
| Other previous medical problem (VTE‐related) | 4 (2.21%) | 6 (2.32%) | 1.02 (0.26–3.62) | 0.978 | 0.94 (0.16–5.61) | 0.946 |
| Current pregnancy | ||||||
| 1st Trimester | 15 (8.29%) | 20 (7.72%) | Reference | – | – | – |
| 2nd Trimester | 37 (20.44%) | 79 (30.50%) | 0.62 (0.29–1.37) | 0.234 | 0.81 (0.28–2.30) | 0.693 |
| 3rd Trimester | 60 (33.15%) | 116 (44.79%) | 0.69 (0.33–1.46) | 0.324 | 0.59 (0.21–1.64) | 0.310 |
| Post‐Partum | 63 (34.81%) | 44 (16.99%) | 1.91 (0.89–4.19) | 0.101 | 1.63 (0.51–5.23) | 0.407 |
| Multiple pregnancy | 4 (2.21%) | 12 (4.63%) | 0.47 (0.13–1.36) | 0.191 | 0.13 (0.01–1.22) | 0.074 |
| Long‐haul travel during pregnancy | 2 (1.10%) | 21 (8.11%) | 0.13 (0.02–0.44) | 0.006 | 0 | 1.0 |
| 3 or more days of immobility/bed rest | 14 (7.73%) | 21 (8.11%) | 0.95 (0.46–1.91) | 0.887 | 0.85 (0.29–2.54) | 0.774 |
| Previous thrombotic event this pregnancy | 5 (2.76%) | 3 (1.16%) | 2.44 (0.59–1.20) | 0.226 | 4.22 (0.49–36.1) | 0.189 |
| Other problems with this pregnancy | 74 (40.88%) | 73 (28.19%) | 1.46 (0.97–2.20) | 0.067 | – | ‐ |
| Other problems with this pregnancy (VTE‐related) | 15 (8.29%) | 19 (7.34%) | 1.14 (0.56–2.31) | 0.713 | 1.05 (0.34–3.17) | 0.938 |