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. 2017 Oct 6;49(6):824–833. doi: 10.1111/ejn.13715

Figure 2.

Figure 2

Optogenetic PPRs in ChIs from control and dopamine‐depleted striata. (A) Averaged EPSCs evoked in ChIs by a pair of 470‐nm light pulses (100‐ms inter‐pulse interval) that activate ChR2‐laden PfN fibers from a control (left) and 6‐OHDA‐lesioned (right) Vglut2‐Cre mouse. (B) Boxplot of PPRs at PfN synapses onto ChIs in control and 6‐OHDA‐lesioned mice. (C) Averaged EPSCs evoked in ChIs by a pair of 470‐nm light pulses that activate ChR2‐laden fibers from a control (left) and 6‐OHDA‐lesioned (right) Thy1‐ChR2 mouse. (D) Boxplot of PPRs at nominally cortical synapses onto ChIs in control and 6‐OHDA‐lesioned mice.