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. 2019 Jan 30;247(4):471–480. doi: 10.1002/path.5205

Figure 2.

PATH-5205-FIG-0002-b

CD40‐, CD40–TRAF6‐ and CD40–TRAF2/3/5‐deficient mice have impaired anti‐MOG IgG production. MOG‐specific IgG concentrations in serum of MHCII–CD40–T2/3/5 −/−, MHCII–CD40–T6 −/−, CD40 −/− and WT mice 16 days after induction (n = 8/group) and 28 days after induction (n = 7/group). Mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001 versus WT.