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. 2019 Feb 5;48(2):82–89. doi: 10.1111/jmp.12399

Figure 2.

Figure 2

CD4CD8 T cells are distinct from CD4 and CD8 T cells in both frequency and function within lung granulomas of M. tuberculosis‐infected macaques. A) CD4CD8 T cells are lower in frequency than CD4 and CD8 T cells. B) CD4CD8 T cells produce less granzyme B than CD4 and CD8 T cells. C and D) Differences in TNF and IL‐10 production in CD4CD8 T cells compared to CD4 and CD8 T cells. Each data point represents an individual lung granulomas. Different symbols represent individual macaques. Kruskal‐Wallis test with Dunn's multiple comparison (post hoc), P‐values shown