Table 1.

The effects of COC and MPH on exocytotic release fraction.

	Control	Cocaine	Methylphenidate
n_intra [103 mole]	168±8	132±7 (−21.43 %**)	123±8 (−26.79 %****)
n_ex [103 mole]	124±5	86±6 (−30.65 %***)	102±7 (−17.74 %**)
Fraction released [%]	74±5	65±5	83±8

[a] The data of n_intra and n_ex are presented as mean of the average number of molecules released±SEM. The SEM of the release fraction was obtained through Monte Carlo simulations. The pairs of data sets were compared using a two‐tailed Wilcoxon–Mann–Whitney rank‐sum test. **, p<0.01; ***, p<0.005; ****, p<0.001.