Table 2.

Current clinical and trial definitions of cardiogenic shock

Clinical definition	SHOCK Trial2	IABP-SHOCK II1	ESC heart failure guidelines6
Cardiac disorder that results in both clinical and biochemical evidence of tissue hypoperfusion	Clinical criteria: MI complicated by left ventricular dysfunction SBP <90 mm Hg for >30 min or support to maintain SBP >90 mm Hg and end-organ hypoperfusion (urine output <30 mL/hour or cool extremities) Haemodynamic criteria: Cardiac Index <2.2 L/min/m2 and PCWP >15 mm Hg	Clinical criteria: Acute MI SBP <90 mm Hg or >30 min or catecholamines to maintain SBP >90 mm Hg and clinical pulmonary congestion and impaired end-organ perfusion (altered mental status, cold/clammy skin and extremities, urine output <30 mL/hour, or lactate >2.0 mmol/L)	Clinical criteria: SBP <90 mm Hg with adequate volume and clinical or laboratory signs of hypoperfusion Clinical hypoperfusion: Cold extremities, oliguria, mental confusion, dizziness, narrow pulse pressure Laboratory hypoperfusion: Metabolic acidosis, elevated serum lactate, elevated serum creatine

ESC, European Society of Cardiology; IABP, intra-aortic balloon pump; MI, myocardial infarction; PCWP, pulmonary capillary wedge pressure; SBP, systolic blood pressure; SHOCK, SHould we emergently revascularise Occluded Coronaries for cardiogenic shocK.