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. 2019 Feb 19;6(1):e000294. doi: 10.1136/lupus-2018-000294

Figure 1.

Figure 1

SLE sera-induced endothelial nitric oxide synthase (eNOS) mRNA expression in human umbilical vein endothelial cells. (A) eNOS mRNA levels from human umbilical vein endothelial cells (HUVECs) treated with buffer 20% control or SLE sera were as follows: for buffer controls (9), 1±0.06918; for healthy controls (14),1.032±0.3294; for SLE (22) 1.888±0.2229 (mean±SEM). (B) Lupus-induced eNOS mRNA levels correlate with patient age but not control derived eNOS mRNA, p<0.01. (C) Lack of association between eNOS mRNA and SLE Disease Activity Index (SLEDAI) scores. (D) Lack of association between NOS3 expression and systolic blood pressure (BP) or diastolic BP measured in millimetre of mercury. *p<0.05, **p<0.001, ***p<0.0001. Samples were analysed using a Kruskal-Wallis non-parametric multiple comparisons test and a Dunn’s post-test and Spearman’s correlation. r=rho value.