Table 1.
Baseline demographics, clinical characteristics and periprocedural results stratified according to 30-day mortality
| Variable | Survivors (n=199) |
Dead (n=19) |
P value |
| Age, years | 82±7 | 80±8 | 0.330 |
| Female | 89(45) | 9 (47) | 0.825 |
| Body surface area, m2 | 1.8±0.2 | 1.7±0.1 | 0.005 |
| Body mass index, kg/m2 | 26±5 | 22±3 | 0.001 |
| STS score | 5.9±3.9 | 8.3±4.4 | 0.012 |
| Euroscore 2 | 9.4±7.2 | 11.3±8.8 | 0.300 |
| NYHA class | 0.527 | ||
| II | 29(15) | 2 (11) | |
| III | 120(60) | 10(53) | |
| IV | 50(25) | 7 (37) | |
| Heart failure | 84(42) | 12(63) | 0.079 |
| Hypertension | 133(67) | 15(79) | 0.280 |
| Atrial dysrhythmia | 89(45) | 11(58) | 0.271 |
| Previous myocardial infarction | 76(38) | 6 (32) | 0.570 |
| Previous PCI | 78(39) | 9 (47) | 0.487 |
| Previous cardiac surgery | 93(47) | 5 (26) | 0.087 |
| LBBB | 18(9) | 2 (11) | 0.831 |
| Peripheral artery disease | 66(33) | 14(74) | <0.000 |
| Porcelain aorta | 21(11) | 5 (26) | 0.043 |
| Cerebrovascular disease | 52(26) | 6 (32) | 0.608 |
| Previous cerebrovascular event | 46(23) | 6 (32) | 0.408 |
| Immunocompromised | 24(12) | 4 (21) | 0.263 |
| Diabetes | 59(30) | 3 (1.5) | 0.201 |
| COPD | 70(35) | 8 (42) | 0.547 |
| eGFR, ml/min/1.73 m2 | 54±20 | 50±24 | 0.055 |
| Previous radiation therapy | 8 (4) | 1 (5) | 0.795 |
| Access | 0.001 | ||
| Transfemoral | 117(59) | 5 (26) | |
| Transaortic | 27(14) | 1 (5) | |
| Transapical | 55(28) | 13(68) | |
| Valve type | 0.206 | ||
| Edwards Sapien | 153(77) | 17(89) | |
| CoreValve | 46(23) | 2 (11) | |
| Periprocedural results | |||
| Intraoperative mortality | − | 6 (2.8) | |
| Myocardial infarction | 3 (1.5) | 3 (16) | <0.000 |
| Cerebrovascular event | 6 (3) | 7 (37) | <0.000 |
| Major or life-threatening bleeding | 5 (2.5) | 5 (26) | <0.000 |
| PVL moderate to severe | 18(9) | 2 (10.5) | 0.085 |
| Permanent PM postoperatively | 17 (8.5) | 0 (0) | − |
Values are mean±SD or n (%)
COPD, chronic obstructive pulmonary disease;LBBB, left bundle branch block;NYHA, New York Heart Association; PCI, percutaneous coronary intervention;PM, pacemaker;PVL, paravalvular leakage;STS, society of thoracic surgeons; eGFR, estimated glomerular filtration rate; eGFR, estimated glomerular filtration rate.