. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: J Allergy Clin Immunol Pract. 2018 Dec 14;7(4):1277–1284. doi: 10.1016/j.jaip.2018.12.004

TABLE II.

Comparison of clinical manifestations between CVID and IgG deficient patients

	CVID (total n = 128)	IgG deficiency (total n = 124)	p value
Infectious manifestations and complications (percentage)
Pneumonia	42.2 (33.6 to 50.8)	39.5 (30.9 to 48.2)	0.67
Recurrent sinusitis	51.6 (42.9 to 60.3)	57.3 (48.5 to 66)	0.37
Bronchiectasis	14.9 (8.66 to 21)	6.45 (2.11 to 10.8)	0.03
Non-infectious complications (percentage)
Autoimmunity (all causes)	39.1 (30.6 to 47.6)	15.3 (8.95 to 21.7)	<0.0001
Autoimmune cytopenias	32.8 (24.6 to 41)	4.84 (1.05 to 8.63)	<0.0001
Interstitial lung disease	7.03 (2.58 to 11.5)	0	0.003
Granulomas	15.6 (9.32 to 21.9)	0.81 (−0.774 to 2.39)	<0.0001
Splenomegaly	20.3 (13.3 to 27.3)	2.42 (−0.301 to 5.14)	<0.0001
Enteropathy	7.03 (2.58 to 11.5)	3.23 (0.106 to 6.35)	0.17
Lymphoid malignancies	3.91 (0.536 to 7.28)	0	0.03
Non infectious complications (any type of complication)	58.6 (50 to 67.2)	25.8 (18.1 to 33.5)	<0.0001