Table 2.
Surface area | Cortical thickness | |||||||
---|---|---|---|---|---|---|---|---|
Cluster | Location | TD | ASD | P-value† | TD | ASD | P-value† | |
Main effect of group | G-1 | Precentral gyrus/planum temporale | 0.256* | 0.326** | 0.337 | −0.403** | −0.297* | 0.251 |
G-2 | Superior–middle temporal gyrus | 0.146 | 0.024 | 0.248 | −0.021 | 0.122 | 0.215 | |
G-3 | Superior parietal lobule/anterior occipital lobe | 0.505** | 0.58** | 0.278 | −0.364** | −0.044 | 0.031 | |
G-4 | Lingual gyrus–calcarine sulcus | 0.324** | 0.412** | 0.287 | −0.292* | −0.316* | 0.440 | |
G-5 | Frontal pole | 0.133 | 0.355** | 0.095 | −0.128 | 0.084 | 0.119 | |
G-6 | Perisylvian, insular, precentral cortex | 0.517** | 0.485** | 0.405 | −0.414** | 0.113 | 0.001 | |
G-7 | Lateral orbitofrontal cortex | 0.185 | −0.031 | 0.115 | −0.363** | −0.260* | 0.264 | |
G-8 | Superior frontal gyrus | 0.107 | 0.119 | 0.472 | −0.424** | −0.340** | 0.295 | |
G-15 | Circular insular sulcus/postcentral sulcus | 0.577** | 0.350 | 0.274 | −0.057 | −0.057 | 1.000 | |
G-16 | Insular cortex/transverse temporal sulcus | 0.157 | 0.253 | 0.707 | −0.446* | −0.099 | 0.155 | |
Interaction | G-12 | Precentral gyrus/central sulcus | 0.337** | 0.256* | 0.312 | −0.164 | −0.135 | 0.436 |
G-13 | Lateral occipital cortex | 0.209 | 0.357** | 0.187 | −0.375** | −0.037 | 0.024 | |
G-14 | Caudal middle frontal gyrus/precentral sulcus | 0.054 | −0.163 | 0.348 | −0.138 | −0.205 | 0.352 | |
G-19 | Frontal pole/anterior cingulate gyrus | 0.462* | 0.399* | 0.776 | −0.375* | −0.239 | 0.573 | |
G-20 | Precuneus cortex | 0.553** | 0.259 | 0.181 | −0.371* | −0.001 | 0.145 | |
G-21 | Superior frontal gyrus–sulcus | 0.383* | 0.287 | 0.685 | −0.234 | 0.105 | 0.198 | |
G-22 | Cuneus cortex | 0.440* | 0.439 | 0.996 | 0.124 | −0.137 | 0.961 |
Correlation analyses were restricted to clusters exhibiting interaction effects or between group differences.
Bold indicates significant difference between groups, uncorrected.
Italics indicate results from NYU sample.
*P < 0.05, **P < 0.01. †P-value corresponds to z-test of between group difference in correlation.