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. Author manuscript; available in PMC: 2019 May 15.
Published in final edited form as: Transfusion. 2017 Oct 8;58(1):168–175. doi: 10.1111/trf.14361

Table 2.

Characteristics of Cardiac Surgery Patientsa

Isolated CAB/Valve Surgery Other Cardiac Surgery
Primary (n = 3,122) Revision (n = 154) P-Value Primary (n = 2,214) Revision (n = 310) P-Value
Age in years, mean ± SD 64 ± 12 63 ± 15 0.396 60 ± 16 54 ± 18 < 0.0001
Male, n (%) 2,226 (71.30%) 107 (69.48%) 0.628 1,376 (62.15%) 191 (61.61%) 0.8553
Comorbiditiesb
 Hypertension, n (%) 2,065 (78.10%) 87 (65.91%) 0.0018 1,204 (63.17%) 163 (59.49%) 0.241
 Pulmonary, n (%) 397 (15.02%) 19 (14.39%) 0.845 342 (17.94%) 32 (11.68%) 0.0073
 Renal, n (%) 398 (15.05%) 18 (13.64%) 0.6524 294 (15.42%) 50 (18.25%) 0.2386
 Coagulopathy, n (%) 150 (5.67%) 18 (13.64%) 0.0011 144 (7.56%) 34 (12.41%) 0.0095
 Obesity, n (%) 484 (18.31%) 22 (16.67%) 0.6304 253 (13.27%) 22 (8.03%) 0.01
 Diabetes, n (%) 771 (29.16%) 29 (21.97%) 0.0678 364 (19.10%) 41 (14.96%) 0.0921
Charlson Comorbidity Index, med (IQR) 2 (1 – 3) 2 (1 – 3) 0.65 2 (1 – 3) 2 (1 – 3) 0.4038
Weight (kg), mean ± SD 87 ± 20 86 ± 20 0.6048 85 ± 21 83 ± 21 0.1037
P2Y12 Inhibitorc, n (%) 412 (13.20%) 21 (13.64%) 0.9518 127 (5.74%) 15 (4.84%) 0.3193
Surgical Characteristics
 Duration of Surgery, min ± SD 257 ± 97 310 ± 106 < 0.0001 281 ± 117 358 ± 142 < 0.0001
 Bypass Time, min ± SD 99 ± 40 134 ± 48 < 0.0001 134 ± 59 182 ± 82 < 0.0001
 Cross Clamp Time, min ± SD 65 ± 26 72 30 0.0014 86 ± 38 105 ± 49 < 0.0001
First Hb, mean ± SD 13.1 ± 2.0 12.6 ± 2.1 0.0021 13.0 ± 2.0 12.5 ± 2.4 0.0004
First Hct, mean ± SD 39.1 ± 5.3 38.0 ± 5.9 0.025 38.9 ± 5.6 37.8 ± 6.2 0.0021
First INR, mean ±SD 1.1 ± 0.4 1.3 ± 1.0 0.0034 1.3 ± 0.7 1.5 ± 1.0 < 0.0001
First PLT, mean ± SD 223 ± 80 211 ± 80 0.092 223 ± 83 208 ± 74 0.0031
% Massively Transfused
 > 5 Units RBC in OR, n (%) 52 (1.67%) 20 (12.99%) < 0.0001 169 (7.63%) 64 (20.65%) < 0.0001
 > 10 Units RBC in OR, n (%) 4 (0.13%) 4 (2.60%) 0.0003 41 (1.85%) 19 (6.13%) < 0.0001

Kg= kilograms; Hb = hemoglobin; Hct= hematocrit; INR= international normalized ratio; PLT= platelet

a

All values are expressed using the number of patients with non-missing data as the denominator

b

ICD-9 and ICD-10 discharge codes available through the Impact Online database were used to identify comorbidities

c

Defined as having received P2Y12 inhibitors within 5 days of surgery