Table 2.
Characteristics of Cardiac Surgery Patientsa
| Isolated CAB/Valve Surgery | Other Cardiac Surgery | |||||
|---|---|---|---|---|---|---|
| Primary (n = 3,122) | Revision (n = 154) | P-Value | Primary (n = 2,214) | Revision (n = 310) | P-Value | |
| Age in years, mean ± SD | 64 ± 12 | 63 ± 15 | 0.396 | 60 ± 16 | 54 ± 18 | < 0.0001 |
| Male, n (%) | 2,226 (71.30%) | 107 (69.48%) | 0.628 | 1,376 (62.15%) | 191 (61.61%) | 0.8553 |
| Comorbiditiesb | ||||||
| Hypertension, n (%) | 2,065 (78.10%) | 87 (65.91%) | 0.0018 | 1,204 (63.17%) | 163 (59.49%) | 0.241 |
| Pulmonary, n (%) | 397 (15.02%) | 19 (14.39%) | 0.845 | 342 (17.94%) | 32 (11.68%) | 0.0073 |
| Renal, n (%) | 398 (15.05%) | 18 (13.64%) | 0.6524 | 294 (15.42%) | 50 (18.25%) | 0.2386 |
| Coagulopathy, n (%) | 150 (5.67%) | 18 (13.64%) | 0.0011 | 144 (7.56%) | 34 (12.41%) | 0.0095 |
| Obesity, n (%) | 484 (18.31%) | 22 (16.67%) | 0.6304 | 253 (13.27%) | 22 (8.03%) | 0.01 |
| Diabetes, n (%) | 771 (29.16%) | 29 (21.97%) | 0.0678 | 364 (19.10%) | 41 (14.96%) | 0.0921 |
| Charlson Comorbidity Index, med (IQR) | 2 (1 – 3) | 2 (1 – 3) | 0.65 | 2 (1 – 3) | 2 (1 – 3) | 0.4038 |
| Weight (kg), mean ± SD | 87 ± 20 | 86 ± 20 | 0.6048 | 85 ± 21 | 83 ± 21 | 0.1037 |
| P2Y12 Inhibitorc, n (%) | 412 (13.20%) | 21 (13.64%) | 0.9518 | 127 (5.74%) | 15 (4.84%) | 0.3193 |
| Surgical Characteristics | ||||||
| Duration of Surgery, min ± SD | 257 ± 97 | 310 ± 106 | < 0.0001 | 281 ± 117 | 358 ± 142 | < 0.0001 |
| Bypass Time, min ± SD | 99 ± 40 | 134 ± 48 | < 0.0001 | 134 ± 59 | 182 ± 82 | < 0.0001 |
| Cross Clamp Time, min ± SD | 65 ± 26 | 72 30 | 0.0014 | 86 ± 38 | 105 ± 49 | < 0.0001 |
| First Hb, mean ± SD | 13.1 ± 2.0 | 12.6 ± 2.1 | 0.0021 | 13.0 ± 2.0 | 12.5 ± 2.4 | 0.0004 |
| First Hct, mean ± SD | 39.1 ± 5.3 | 38.0 ± 5.9 | 0.025 | 38.9 ± 5.6 | 37.8 ± 6.2 | 0.0021 |
| First INR, mean ±SD | 1.1 ± 0.4 | 1.3 ± 1.0 | 0.0034 | 1.3 ± 0.7 | 1.5 ± 1.0 | < 0.0001 |
| First PLT, mean ± SD | 223 ± 80 | 211 ± 80 | 0.092 | 223 ± 83 | 208 ± 74 | 0.0031 |
| % Massively Transfused | ||||||
| > 5 Units RBC in OR, n (%) | 52 (1.67%) | 20 (12.99%) | < 0.0001 | 169 (7.63%) | 64 (20.65%) | < 0.0001 |
| > 10 Units RBC in OR, n (%) | 4 (0.13%) | 4 (2.60%) | 0.0003 | 41 (1.85%) | 19 (6.13%) | < 0.0001 |
Kg= kilograms; Hb = hemoglobin; Hct= hematocrit; INR= international normalized ratio; PLT= platelet
All values are expressed using the number of patients with non-missing data as the denominator
ICD-9 and ICD-10 discharge codes available through the Impact Online database were used to identify comorbidities
Defined as having received P2Y12 inhibitors within 5 days of surgery