Table 2^a.

Table 2A Abundance of Nup358, Bicd2 and Rab6 in human organisms, normalized to Nup358
Human dataset (quality score)	Nup358		Rab6	BicD2
Human peptide atlas 2014 (26.0)	1		2.5	0.4
Global proteome machine 2014 (23.9)	1		11.0	0.4
Integrated Human Proteome (15.5)	1		6.4	0.4
Average ratio	1		6.6 ± 4.3	0.4 ± 0
		BicD1	BicDRI	BicDR2	α&β Tubulin
Human peptide atlas 2014 (26.0)		0.05	0	0.08	307
Global proteome machine 2014 (26.0)		0.11	0	0.05
Integrated human proteome (26.0)		0.03	0	0.06	698
Average ratio		0.06 ± 0.04	0	0.06 ± 0.02	503 ± 200
Table 2B Cytosolic concentration of human Nup358, BicD2 and Rab6
	Nup358 G1 phase	Rab6	BicD2	BicD1 & BicDR2	α&β Tubulin (Control)
Molecules per cell	32000	211000	13000	4000	1.5*107
Cytosolic conc. (nM)	40	268	16	5	20000

^aData was obtained from the protein abundance database.⁵⁵ The protein abundance data quality score is based on the assumption that interacting proteins from a complex have a tendency to have similar abundance, and a large score indicates high data quality. All available data sets from whole human organisms were used, which reported abundance for all three proteins.^55,67,68 As a control, the cellular concentration of αβ-tubulin combined was calculated using the same method, which fits well with the cellular concentration of tubulin reported in the literature (e.g., 25 μM and 12−18 μM^58–60).