Table 4.
Summary of 6-week change scores in quality of life and neurological outcomes measures.
| Variable | Lidocaine (mean ± SD) | Placebo (mean ± SD) | P-Value* | |
|---|---|---|---|---|
| Quality of Life | CESD (−) | 0.57 ± 7.5 | 0.16 ± 8.3 | >0.999 |
| DASI (+) | −10.98 ± 15.4 | −11.67 ± 16.8 | >0.999 | |
| STAI (−) | −7.12 ± 12.1 | −6.31 ± 11.4 | >0.999 | |
| Symptoms Limitation (−) | −0.67 ± 4.0 | −0.80 ± 3.9 | >0.999 | |
| OARS-IADL (−) | 2.46 ± 4.2 | 2.10 ± 3.9 | >0.999 | |
| Cognitive Difficulties (−) | −3.00 ± 14.6 | −3.21 ± 15.9 | >0.999 | |
| Social Activities (−) | 0.95 ± 3.4 | 1.59 ± 3.2 | 0.084 | |
| Social Support (+) | 1.23 ± 14 | −0.49 ± 13.9 | 0.814 | |
| Work Activities (−) | 2.71 ± 4.9 | 3.00 ± 4.3 | >0.999 | |
| General Health Perception (−) | −0.004 ± 1.3 | −0.03 ± 1.2 | >0.999 | |
| Neurologic Outcomes | NIHSS (−) | 0.05 ± 0.5 | 0.04 ± 0.5 | >0.999 |
| WPNS (+) | 0.04 ± 1.1 | −0.01 ± 1.3 | >0.999 | |
A minus sign (−) indicates that a lower score is better; a plus sign (+) indicates that a higher score is better. CESD: Center for Epidemiologic Studies – Depression Scale, DASI: Duke Activity Status Index, STAI: State Trait Anxiety Inventory, OARS-IADL: Duke Older American Resources Services Procedures – Instrumental Activities of Daily Living, NIHSS: National Institutes of Health Stroke Scale, WPNS: Western Perioperative Neurologic Scale.
*
Adjusted for multiple comparisons.