Table 5.
Summary of 1-year change scores in quality of life and neurological outcomes measures.
| Variable | Lidocaine (mean ± SD) | Placebo (mean ± SD) | P-Value* | |
|---|---|---|---|---|
| Quality of Life | CESD (−) | −1.27 ± 7.7 | −0.89 ± 7.9 | >0.999 |
| DASI (+) | 6.3 ± 18.3 | 6.96 ± 16.9 | >0.999 | |
| STAI (−) | −6.7 ± 12.7 | −6.39 ± 10.3 | >0.999 | |
| Symptoms Limitation (−) | −1.39 ± 3.8 | −1.48 ± 3.8 | >0.999 | |
| OARS-IADL (−) | −0.15 ± 2.1 | −0.31 ± 2.6 | >0.999 | |
| Cognitive Difficulties (−) | −0.46 ± 16.1 | −1.02 ± 17 | >0.999 | |
| Social Activities (−) | −0.2 ± 3.2 | 0.03 ± 3.4 | >0.999 | |
| Social Support (+) | 0.71 ± 13.4 | −1.16 ± 12.9 | 0.696 | |
| Work Activities (−) | −1.37 ± 4.3 | −1.42 ± 4.1 | >0.999 | |
| General Health Perception (−) | −0.28 ± 1.2 | −0.43 ± 1.1 | >0.999 | |
| Neurologic Outcomes | NIHSS (−) | 0.05 ± 0.7 | 0.07 ± 0.6 | >0.999 |
| WPNS (+) | 0.02 ± 1.1 | −0.02 ± 1.2 | >0.999 | |
A minus sign (−) indicates that a lower score is better; a plus sign (+) indicates that a higher score is better. CESD: Center for Epidemiologic Studies – Depression Scale, DASI: Duke Activity Status Index, STAI: State Trait Anxiety Inventory, OARS-IADL: Duke Older American Resources Services Procedures – Instrumental Activities of Daily Living, NIHSS: National Institutes of Health Stroke Scale, WPNS: Western Perioperative Neurologic Scale.
*
Adjusted for multiple comparisons.