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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Cerebellum. 2019 Jun;18(3):448–456. doi: 10.1007/s12311-019-01012-w

Figure 3. Elevated levels of DNA damage in AOA2 patient germ cells compared to control.

Figure 3.

Increased levels of DNA breaks are shown by immunostaining with anti-γH2AX (pSer139 H2AX) antibody were detected in AOA2 patient germ cells and Setx−/− seminiferous tubules as compared to Control and Setx+/+. Both low and high magnification images are shown with scale bars of 100μm and 20μm, respectively. Nuclei were stained with DAPI.