Figure 5. Elevated levels of germ cells apoptosis in an AOA2 patient.
A. TUNEL-stained testis sections from control, AOA2 patient and adult Setx+/+ and Setx−/− mice. White arrow indicates TUNEL-positive germ cells. DAPI was used to stain nuclei. Scale bar, 20 μm. B. Quantitation of the number of apoptotic tubules (tubules containing ≥ 1 TUNEL positive cell). More than 200 tubules were scored for each sample.