Table 1.

Polarizable force fields for biomolecules and available software

Force field	Polarization	Electrostatics		Coverage					Software
		Penetration	Anisotropy	Protein	DNA	RNA	Sugar	Lipid
AMBER	Induced dipole	N/A	N/A	Yes	Yes	Yes	No	No	AMBER
AMOEBA	Induced dipole	N/A	Multipole	Yes	Yes	Yes	No	Yes	TINKER, AMBER, OpenMM
CHARMM-Drude	Drude	N/A	Distributed charges	Yes	Yes	No	Yes	Yes	CHARMM, NAMD, AMBER, GROMACS, OpenMM
CHARMM-FQ	Fluctuating charge	N/A	N/A	Yes	No	No	No	Yes	CHARMM
SIBFA	Induced dipole	Yes	Multipole	Yes	No	No	No	No	TINKER
ABEEMσπ	Fluctuation charge	N/A	Distributed charges	Yes	Yes	No	No	No	TINKER