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. Author manuscript; available in PMC: 2020 May 14.
Published in final edited form as: Lab Chip. 2019 May 14;19(10):1877–1886. doi: 10.1039/c8lc01279b

Fig. 4.

Fig. 4

a) Characterization of the performance of on-demand photo-release of captured exosomes from immunomagnetic beads. The positive control is a fluorescence-labeled antibody captured by photo-release immunomagnetic beads. The negative control is the immunomagnetic beads without a photo-cleavable linker. b) The SEM image of the surface of photo-release immunomagnetic beads captured with exosomes. Exosome particles were seen as the cup shape due to the vacuum sample preparation. c) The SEM image of the surface of photo-release immunomagnetic beads after photocleavage. d) Characterization of UV exposure time influence on photo-cleavage efficiency. The error bar shows the three repeats with average measurement (RSD < ~5%). e) Nanoparticle tracking analysis of exosome size distribution between photo-released, surface engineered exosomes and native exosomes.