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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Curr Obes Rep. 2019 Jun;8(2):156–164. doi: 10.1007/s13679-019-00335-3

Figure 1.

Figure 1.

Mechanisms by which metformin impacts obesity, appetite, and weight loss. CNS: central nervous system, AgRP: Agouti-related peptide, AMPK: AMP-activated protein kinase, NTS: nucleus tractus solitarius, SCFA: short chain fatty acids, GLP-1: glucagon like peptide-1, PYY: peptide YY.