Number of sensors |
Minimal number of sensors easy-to-access location/s |
Number of sensors locations based on clinical purpose |
Number location of sensors based on targeted accuracy |
Sensor burden |
Minimal patient caregiver burden over a long time |
Minimal clinician burden over a long time |
Potentially greater burden in patients clinicians over a short time |
Frequency |
Less frequent use to enhance adherence during data capture |
Frequency depending on use of data |
More frequent use to ensure, e.g., high signal to noise ratio |
Targets |
1–2 domains at low- frequency intervals, based on identified problems |
Possibly 1–2 domains at periodic intervals, according to patient’s clinician’s goals |
Likely multiple domains at frequent intervals, according to research objectives |
User friendliness |
Easy to use, ready (ideally 24/7) access to helpdesk to facilitate compliance minimal manual skill level required to operate the system. |
Easy to use in clinical practice; helpdesk to troubleshoot range of potential problems. Facilitate patient compliance by reviewing data. |
Usability compliance – less of an issue for fully supervised sessions; will have to ensure ease of use to facilitate patient compliance for unsupervised monitoring |
Supervised vs. unsupervised |
Unsupervised data collection ensured by friendly, acceptable device to user |
Reliance only on unsupervised data collection |
Reliance on supervised unsupervised data collection |
Desirable technical aspects |
Long battery life, low charging, easy or automatic uploading downloading, small size, low weight, water-proof. Low level of expertise to use underst output. |
Battery life, need for charging, size, weight less critical for supervised /short duration sessions. High level of expertise to analyze. |
Validation |
Must show correlation with global patient-centered scales for the appropriate domains. |
Monitoring of motor fluctuations medication titration. |
May not strongly correlate with the total or even specific items of such gold stards as the UPDRS. Observation or video analysis may be needed. |