Table 1.
Description of Study Population
| Low-grade Prostate Cancer (n=40) | High-grade Prostate Cancer (n=26) | P-value | |
|---|---|---|---|
| Median age, years (n; range) | 63.5 (40; 46-79) | 65 (26; 47-86) | 0.16 |
| Median BMI, kg/m2 (n; 25-75 percentile) | 28.4 (39; 25.8-34.2) | 27.9 (25; 25.8-30.5) | 0.44 |
| Race % (n) | -------------- | ||
| White | 62.5 (25/40) | 73.1 (19/26) | |
| Black | 20 (8/40) | 15.4 (4/26) | |
| Asian | 7.5 (3/40) | 7.7 (2/26) | |
| Other | 10 (4/40) | 3.9 (1/26) | |
| Ethnicity % (n) | 0.39 | ||
| Non-Hispanic | 87.5 (35/40) | 96.2 (25/26) | |
| Hispanic | 12.5 (5/40) | 3.9(1/26) | |
| Education % (n) | 1.00 | ||
| ≤ 11 years | 7.9 (3/38) | 4 (1/25) | |
| ≥ 12 years | 92.1 (35/38) | 96 (24/25) | |
| Ever smoked cigarettes % (n) | 0.94 | ||
| Yes | 62.5 (35/40) | 61.5 (16/26) | |
| No | 37.5 (15/40) | 38.5 (10/26) | |
| BPH % (n) | 1.00 | ||
| Yes | 7.5 (3/40) | 4 (1/25) | |
| No | 92.5 (37/40) | 96.0 (24/25) | |
| Prostatitis % (n) | 0.20 | ||
| Yes | 5.0 (2/40) | 15.4 (4/26) | |
| No | 95.0 (38/40) | 84.6 (22/26) | |
| ASAP/atypia % (n) | 0.16 | ||
| Yes | 27.6 (8/29) | 9.1 (2/22) | |
| No | 72.4(21/29) | 90.9 (20/22) | |
| HGPIN % (n) | 0.30 | ||
| Yes | 3.5 (1/29) | 13.6 (3/22) | |
| No | 96.6 (28/29) | 86.4 (19/22) | |
| Family history of prostate cancer % (n) | 0.29 | ||
| Yes | 20.6 (7/34) | 8.7 (2/23) | |
| No | 79.4 (27/34) | 91.3 (21/23) | |
| Median serum PSA, ng/mL (n; 25-75 percentile) | 5 (39; 4.2-7.13) | 10.0 (26; 6.6-20.5) | <0.01 |
Note: BMI, body mass index; BPH, benign prostatic hyperplasia; ASAP, atypical small acinar proliferation; HGPIN, high-grade prostatic intraepithelial neoplasia; PSA, prostate-specific antigen; statistically significance between low- and high-grade prostate cancer at P-value ≤ 0.05.