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. Author manuscript; available in PMC: 2019 May 16.
Published in final edited form as: Mol Psychiatry. 2018 Nov 15;25(9):2119–2129. doi: 10.1038/s41380-018-0276-1

Fig. 2.

Fig. 2.

(a) Functional connectivity among the subject-specific ROIs can predict the PANSS negative subscale scores in 76 patients with schizophrenia or schizoaffective disorder. The scatterplot illustrates the correlation (r = 0.35, p = 0.033, permutation test) between the predicted and observed PANSS negative scores. (b) Fifteen connections that are predictive of the PANSS negative scores are plotted on the wheel. Functional regions involved in the most predictive connections are rendered on the cortical surface. (c) A similar analysis is performed using 116 ROIs defined in a group-level network template. Functional connectivity based on the brain template is not able to predict the PANSS negative scores in these patients (r = 0.03, p = 0.403, permutation test).