Table 1. SNV, indel, and CNA overlap of clinical report between FF and FFPE.
| Sample | Tier | Total | Unique FF | Unique FFPE | Overlap | % Overlap |
|---|---|---|---|---|---|---|
| 4 | 1 | 6 (2/4) | 1 (0/1) | 0 (0/0) | 5 (2/3) | 83 (100/75) |
| 4 | 2 | 8 (4/4) | 1 (1/0) | 0 (0/0) | 7 (3/4) | 88 (75/100) |
| 4 | 3 | 2 (2/0) | 0 (0/0) | 1 (1/0) | 1 (1/0) | 50 (50/NA) |
| 32 | 1 | 4 (2/2) | 0 (0/0) | 0 (0/0) | 4 (2/2) | 100 (100/100) |
| 32 | 2 | 17 (17/0) | 1 (1/0) | 3 (3/0) | 13 (13/0) | 76 (76/NA) |
| 32 | 3 | 7 (5/2) | 1 (0/1) | 3 (3/0) | 3 (2/1) | 43 (40/50) |
| 65 | 1 | 11 (1/10) | 0 (0/0) | 0 (0/0) | 11 (1/10) | 100 (100/100) |
| 65 | 2 | 12 (10/2) | 0 (0/0) | 1 (1/0) | 11 (9/2) | 92 (90/100) |
| 65 | 3 | 11 (7/4) | 1 (0/1) | 1 (1/0) | 9 (6/3) | 82 (86/75) |
| 300 | 1 | 8 (2/6) | 0 (0/0) | 0 (0/0) | 8 (2/6) | 100 (100/100) |
| 300 | 2 | 16 (14/2) | 0 (0/0) | 2 (2/0) | 14 (12/2) | 88 (86/100) |
| 300 | 3 | 6 (6/0) | 0 (0/0) | 1 (1/0) | 5 (5/0) | 83 (83/NA) |
| 365 | 1 | 11 (2/9) | 0 (0/0) | 0 (0/0) | 11 (2/9) | 100 (100/100) |
| 365 | 2 | 11 (8/3) | 1 (1/0) | 0 (0/0) | 10 (7/3) | 91 (88/100) |
| 365 | 3 | 10 (4/6) | 0 (0/0) | 0 (0/0) | 10 (4/6) | 100 (100/100) |
| Total | 1 | 40 (9/31) | 1 (0/1) | 0 (0/0) | 39 (9/30) | 98 (100/97) |
| Total | 2 | 64 (53/11) | 3 (3/0) | 6 (6/0) | 55 (44/11) | 86 (83/100) |
| Total | 3 | 36 (24/12) | 2 (0/2) | 6 (6/0) | 28 (18/10) | 78 (75/83) |
CNA, copy-number alteration; FF, fresh frozen; FFPE, formalin-fixed, paraffin-embedded; NA, not applicable (no variant detected in this category); SNV, single-nucleotide variants. Total (somatic SNV+indel/somatic CNA).