Table 1. Clinical and demographic data in the study groups.
| Parametera | Control group (n=24) | DM group (n=26) | POAG group (n=16) | POAG+DM group (n=21) | Pa |
| Age (y) | 72.33±11.26 | 69.04±9.46 | 75.69±5.54 | 59.95±3.89a | <0.05 |
| Sex ratio (M:F) | 1:2 | 1:1.16 | 2:1 | 2:1 | 0.873 |
| IOP (mm Hg) | 14.21±2.68 | 15.50±1.9 | 18.19±4.3 | 20.33±2.3a | 0.05 |
| Anti-glaucoma substances (number) | - | - | 3±0.87 | 2.85±1.02 | 0.48 |
| Glaucoma therapy | |||||
| Treated eyes | 16 (100) | 21 (100) | |||
| Active substance | |||||
| BB | 11 (68) | 16 (76) | 0.129 | ||
| PGA | 16 (100) | 21 (100) | - | ||
| AA | 3 (18.75) | 4 (19) | 0.891 | ||
| CAI | 5 (31) | 9 (42) | 0.093 | ||
| Number of drops | |||||
| 1 | 2 (12.5) | 3 (14.2) | 0.681 | ||
| ≥2 | 14 (87.5) | 18 (85.8) | 0.462 | ||
| MD (dB) | - | - | -10.59±8.35 | -8.13±7.9 | 0.083 |
| PSD (dB) | - | - | 3.25±4.22 | 2.05±0.90a | 0.260 |
| Duration of glaucoma (mo) | - | - | 45.63±26.48 | 36.86±15.86 | 0.581 |
| Duration of diabetes (mo) | - | 133.56±77.82 | - | 115.62±81.24 | 0.119 |
| Blood sugar level (mg/dL) | - | 177.12±19.54 | - | 155.05±21.83 | 0.127 |
| HbA1c (%) | - | 8.12±1.81 | - | 7.09±1.35 | 0.095 |
IOP: Intraocular pressure; BB: Beta blocker; PGA: Prostaglandin analogue; AA: Alpha agonists; CAI: Carbonic anhydrase inhibitors; MD: Mean deviation; PSD: Pattern standard deviation; HbA1c: Glycosylated hemoglobin; SD: Standard deviation. aSignificance of differences between groups: χ2 test, two samples independent t-test or Mann-Whitney U test.
mean±SD, n (%)