Table 2.
Comparison of the patients with low and high 15D score (n = 108)a
| Variable | Low (≤0.817) n = 54 | High (>0.817) n = 54 | p value |
|---|---|---|---|
| Age, y | 72.0 (62.8–80.0) | 68.0 (60.5–75.0) | 0.035 |
| Male | 29 (53.7) | 31 (57.4) | 0.699 |
| Agreement by proxy | 27 (50.0) | 6 (11.1) | <0.001 |
| mRS 3–5 prior to ICH | 2 (3.7) | 0 (0.0) | 0.495 |
| Diabetes | 9 (16.7) | 7 (13.0) | 0.588 |
| History of ischemic stroke | 8 (14.8) | 7 (13.0) | 0.781 |
| History of any ICH | 6 (11.1) | 1 (1.9) | 0.113 |
| COPD or asthma | 6 (11.1) | 2 (3.7) | 0.270 |
| Dementia | 3 (5.6) | 0 (0.0) | 0.243 |
| Coronary artery disease | 6 (11.1) | 3 (5.6) | 0.489 |
| Atrial fibrillation | 16 (29.6) | 11 (20.4) | 0.267 |
| Chronic heart failure | 6 (11.1) | 1 (1.9) | 0.113 |
| History of cancer | 10 (18.5) | 14 (25.9) | 0.355 |
| Antiplatelet treatment | 11 (20.4) | 10 (18.5) | 0.808 |
| Anticoagulant treatment | 14 (25.9) | 9 (16.7) | 0.240 |
| Antihypertensive medication | 34 (63.0) | 23 (42.6) | 0.034 |
| Antidepressant medication | 3 (5.6) | 0 (0.0) | 0.243 |
| Sad or depressed for more than 2 weeks during the year prior to ICHb | 8 (19.0) | 10 (19.6) | 0.946 |
| Any alcohol use (within 1 year prior ICH)b | 44 (84.6) | 41 (77.4) | 0.344 |
| No or little stress at homeb | 37 (75.5) | 43 (84.3) | 0.271 |
| Living alone | 20 (37.0) | 11 (20.4) | 0.056 |
| Married or registered relationshipb | 31 (59.6) | 38 (70.4) | 0.246 |
| Occupational status, working | 9 (16.7) | 15 (27.8) | 0.165 |
| High education (Master or Bachelor's degree)b | 9 (17.6) | 22 (41.5) | 0.008 |
| NIHSS on admission | 9.0 (3.8–15.5) | 3.0 (2.0–5.0) | <0.001 |
| GCS on admission | 14.5 (13.0–15.0) | 15.0 (15.0–15.0) | <0.001 |
| Baseline ICH volume, mL | 13.6 (6.2–24.5) | 4.5 (1.7–16.0) | 0.002 |
| ICH location | 0.202 | ||
| ICH location, lobar | 11 (20.4) | 20 (37.0) | |
| ICH location, deep supratentorial | 39 (72.2) | 31 (57.4) | |
| ICH location, infratentorial | 4 (7.4) | 3 (5.6) | |
| Any neurosurgery | 5 (9.3) | 0 (0.0) | 0.057 |
| DNR orders in hospital | 14 (25.9) | 2 (3.7) | 0.001 |
| Deterioration (increase in NIHSS at least 4 points) within 1 week of ICH | 5 (9.3) | 1 (1.9) | 0.205 |
| Acute myocardial infarction or heart failure within 1 week of ICH | 2 (3.7) | 0 (0.0) | 0.495 |
| mRS at 3 months | <0.001 | ||
| mRS 0 | 0 (0.0) | 4 (7.4) | |
| mRS 1 | 2 (3.7) | 11 (20.4) | |
| mRS 2 | 14 (25.9) | 33 (61.1) | |
| mRS 3 | 15 (27.8) | 4 (7.4) | |
| mRS 4 | 13 (24.1) | 2 (3.7) | |
| mRS 5 | 10 (18.5) | 0 (0.0) | |
| Barthel Index at 3 months | 92.5 (53.8–100.0) | 100 (100.0–100.0) | <0.001 |
| Living at home at 3 months | 33 (61.1) | 52 (96.3) | <0.001 |
| Working at 3 months | 1 (1.9) | 3 (5.6) | 0.618 |
Data are n (%), mean (SE), or median (IQR).
mRS: modified Rankin Scale; ICH: intracerebral hemorrhage; COPD: chronic obstructive pulmonary disease; NIHSS: the National Institutes of Health Stroke Scale; GCS: Glasgow Coma Scale; DNR: do not resuscitate.
a
n = 16 exclusion due to incomplete answers.
b
Missing data for BMI in four patients (3.7%), sad or depressed for more than 2 weeks in 15 patients (13.9%), alcohol use in three patients (2.8%), no or little stress at home in eight patients (7.4%), marital status in three patients (1.9%), high education in four patients (3.7%).
The bold values indicate P < 0.05.