Use of risperidone in children is common, especially among children with developmental and behavioral problems such as autism and attention-deficit/hyperactivity disorder.

Nearly one in three pediatric patients treated with risperidone experienced one or more adverse event. Weight gain and extrapyramidal symptoms were the most common adverse events.

The pre-exposure presence of self-injurious behavior was associated with higher odds of adverse events, whereas concomitant use of antibiotics was associated with lower odds of adverse events.