Table 2.

Statistics of the TCR and BCR sequences.

Items	Patient 1		Patient 2		Health control
	TCR	BCR	TCR	BCR	TCR	BCR
Total reads number	632248	486372	709147	565148	1078038	466662
immune sequences number	625772	478308	702605	556630	1069580	462368
Unknown sequences number	6476	8064	6542	8518	8458	4294
productive sequences number	445475	376731	522948	457868	809132	361462
Non_productive sequences number	180297	101577	179657	98762	260448	100906
In-frame sequences number	464924	400538	549989	483511	841639	385295
Out-of_frame sequences number	157489	77377	149177	72843	223826	76805
Total CDR3 sequences number	431848	354183	513044	428262	795732	349989
Unique cdr3 nt sequences number	23920	18066	21255	20420	46012	32346
Unique cdr3 aa sequences number	19120	12554	16783	14287	37531	24048
Highly expended clone number all	1	36	8	33	6	0
Highly expended clone ratio all	0.006097053	0.253643	0.108823025	0.247577	0.077371527	0
Shannon entropy all	0.599300084	0.515524	0.519455186	0.50069	0.601856778	0.656329