Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 15;10:2138. doi: 10.1038/s41467-019-10148-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — TC analysis between MET500 breast cancer samples and CCLE breast cancer cell lines. a In total, 1019 CCLE cell lines are ranked according to their transcriptome similarity with MET500 breast cancer samples. Each dot is a CCLE cell line and breast cancer cell lines are marked by red. b Metastatic-site-specific TC analysis results are highly correlated between liver and lymph node. Each dot is a CCLE breast cancer cell line, with x-axis representing its transcriptome similarity with the nine lymph-node-derived MET500 breast cancer samples, and y-axis representing its transcriptome similarity with the 27 liver-derived MET500 breast cancer samples. c t-SNE plot of MET500 breast cancer samples. Metastatic-sites are labeled by color and subtypes are labeled by shape. d Pair-wise comparison of subtype-specific TC analysis results. In the lower-left plots, each dot is a CCLE breast cancer cell line, with the two axis representing transcriptome similarity of the cell line with MET500 breast cancer samples of the two intersecting subtypes. The upper-right shaded values are the corresponding pair-wise spearman rank correlation values of each pair. Source data are provided as a Source Data file