TABLE 1.
Challenge participant demographics, clinical results, and preexisting antibody titers
| Characteristica | Value for characteristic | ||
|---|---|---|---|
| Mean age, yr (range) | 27 (18–47) | ||
| Sex | Male | Female | |
| No. of participants (%) | 44 (53.0) | 39 (47.0) | |
| Race | Asian | Black | White |
| No. of participants (%) | 5 (6.0) | 35 (41.7) | 43 (51.1) |
| Group | No MMID | MMID | |
| No. of participants | 39 | 44 | |
| Mean max symptom score (range) | 1.8 (0–7) | 5.6 (1–14) | |
| Mean no. of days of symptoms (range) | 3.6 (0–34) | 6.8 (2–11) | |
| Mean no. of days of shedding (range) | 0.15 (0–2) | 3.7 (1–9) | |
| Pre NAI titers (GMT) | 258.5 | 47.7 | |
| Pre HAI titers (GMT) | 22.4 | 4.2 | |
| Pre HA stalk titers (mean) | 66,227 | 30,430 | |
| Quartile | Lower quartile (Q1) | Median quartile (Q2) | Upper quartile (Q3) |
| Max symptom score | 1 | 3 | 6 |
| No. of days of symptoms | 3 | 5 | 7.75 |
| No. of days of shedding | 0 | 1 | 4 |
| Pre NAI titers (GMT) | 80 | 160 | 320 |
| Pre HAI titers (GMT) | 0 | 10 | 80 |
| Pre HA stalk titers (mean) | 23,605.5 | 52,014.5 | 82,366.5 |
a
max, maximum; Pre, preexisting (baseline).