Table 1.

Predictive TPPU metabolites.

Compound ID	Structure	Available authentic standard
TPPU		+
M1		+
M2		+
M3		+
M4		+
α-Keto amide		+
Aniline		+
1		–
2		–
3		–
4		–
5		–
6		–
7		–
8		–
9		–
10		–
11		–
12		–
13		–
14		–

M1–M4 are detectable metabolites. α-Keto amide, aniline, and 1–14 are possible degradation products of TPPU not detected in vitro and in vivo.

⁺Standard available.

⁻Standard not available.