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. 2019 Jan 2;121(3):881–892. doi: 10.1152/jn.00536.2018

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Fig. 10. — The increase in miniature excitatory postsynaptic currents (mEPSCs) is eliminated in TRPV1^−/− mice after chronic intermittent hypoxia (CIH). A and B: examples of mEPSCs under normoxia (NORM) and CIH in TRPV1^+/+ (A) and TRPV1^−/− (B) mice. Note the increase in mEPSCs after CIH in TRPV1^+/+ mice but not TRPV1^−/− mice. Examples are from a single trace. C: compared with NORM (N), mEPSCs increased in TRPV1^+/+ mice after CIH. On the other hand, mEPSCs did not increase in TRPV1^−/− mice after CIH (2-way ANOVA: mouse, P = 0.34; hypoxia, P = 0.29; mouse × hypoxia, P = 0.11). *P < 0.05, CIH vs. NORM with Bonferroni post hoc (TRPV1^+/+: NORM, n = 10; CIH, n = 17; TRPV1^−/−: NORM, n = 8; CIH, n = 4).