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. 2019 May 14;5(5):e01710. doi: 10.1016/j.heliyon.2019.e01710

Fig. 12.

Fig. 12

Effects of tBHQ, PQ, thiamine BFT and SuBT on viability and luminescence of a Nrf2/ARE luciferase reporter 3T3 stable cell line. A) Protective effects of thiamine, BFT and SuBT against PQ-induced cell death. B) Effects of PQ and tBHQ on Nrf2/ARE activation (24-h incubation). C) Effects of thiamine, BFT and SuBT on Nrf2/ARE activation (24 h incubation). D) Combination of PQ and thiamine, BFT and SuBT on Nrf2/ARE activation. Thiamine and precursors were added 1 h prior to PQ. One-way ANOVA followed by Dunnett's multiple comparisons test (B and C). One-way ANOVA followed by Tukey's multiple comparisons test (A and D).