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. 2019 Apr 24;11(4):579. doi: 10.3390/cancers11040579

Table 3.

Marginal analysis of overall survival: identified main effects and interactions, with raw p-values Pr and false discovery rate (FDR) adjusted p-values Pa.

Feature Group Feature Name Estimate Pr Pa
Holistic Threshold_FinalThreshold_Identifyeosinprimarycytoplasm Main −0.301 0 0.095
Holistic Threshold_OrigThreshold_Identifyeosinprimarycytoplasm Main −0.301 0 0.095
Holistic Threshold_WeightedVariance_identifyhemaprimarynuclei Main −0.360 0 0.077
Geometry AreaShape_Area Smoking 0.253 0.004 0.078
Geometry AreaShape_MaximumRadius Smoking 0.266 0.004 0.074
Geometry AreaShape_MeanRadius Smoking 0.265 0.005 0.079
Geometry AreaShape_MedianRadius Smoking 0.266 0.005 0.079
Geometry AreaShape_MinFeretDiameter Smoking 0.257 0.003 0.073
Geometry AreaShape_MinorAxisLength Smoking 0.264 0.002 0.07
Geometry AreaShape_Zernike_4_4 Smoking −0.241 0.005 0.079
Geometry AreaShape_Zernike_7_3 Smoking −0.308 0 0.027
Geometry AreaShape_Zernike_8_4 Smoking −0.242 0.007 0.096
Geometry AreaShape_Zernike_8_6 Smoking −0.252 0.005 0.079
Geometry AreaShape_Zernike_9_1 Smoking −0.303 0 0.027
Texture Granularity_13_ImageAfterMath.1 Smoking −0.317 0.001 0.054
Texture Mean_Identifyeosinprimarycytoplasm_Texture_Correlation_maskosingray_3_03 Smoking 0.232 0.005 0.079
Geometry Mean_Identifyhemasub2_AreaShape_Area Smoking 0.297 0.001 0.049
Geometry Mean_Identifyhemasub2_AreaShape_MaximumRadius Smoking 0.318 0.001 0.049
Geometry Mean_Identifyhemasub2_AreaShape_MeanRadius Smoking 0.318 0.001 0.049
Geometry Mean_Identifyhemasub2_AreaShape_MedianRadius Smoking 0.308 0.002 0.054
Geometry Mean_Identifyhemasub2_AreaShape_MinFeretDiameter Smoking 0.299 0.001 0.049
Geometry Mean_Identifyhemasub2_AreaShape_MinorAxisLength Smoking 0.310 0.001 0.045
Geometry Mean_Identifyhemasub2_AreaShape_Zernike_4_4 Smoking −0.263 0.003 0.07
Geometry Mean_Identifyhemasub2_AreaShape_Zernike_5_1 Smoking −0.268 0.002 0.07
Geometry Mean_Identifyhemasub2_AreaShape_Zernike_8_2 Smoking −0.277 0.003 0.073
Geometry Mean_Identifyhemasub2_AreaShape_Zernike_8_8 Smoking −0.290 0.003 0.073
Geometry Mean_Identifyhemasub2_AreaShape_Zernike_9_1 Smoking −0.226 0.004 0.074
Texture Mean_Identifyhemasub2_Granularity_13_ImageAfterMath Smoking −0.325 0.001 0.054
Texture Mean_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_01 Smoking 0.330 0 0.039
Texture Mean_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_02 Smoking 0.297 0.002 0.07
Texture Mean_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_03 Smoking 0.397 0 0.01
Texture Mean_Identifyhemasub2_Texture_SumVariance_ImageAfterMath_3_02 Smoking 0.258 0.007 0.093
Texture Median_Identifyeosinprimarycytoplasm_Texture_Correlation_maskosingray_3_03 Smoking 0.233 0.004 0.079
Geometry Median_Identifyhemasub2_AreaShape_Area Smoking 0.344 0 0.027
Geometry Median_Identifyhemasub2_AreaShape_MaxFeretDiameter Smoking 0.242 0.005 0.079
Geometry Median_Identifyhemasub2_AreaShape_MaximumRadius Smoking 0.323 0.001 0.049
Geometry Median_Identifyhemasub2_AreaShape_MeanRadius Smoking 0.323 0.001 0.049
Geometry Median_Identifyhemasub2_AreaShape_MedianRadius Smoking 0.266 0.005 0.079
Geometry Median_Identifyhemasub2_AreaShape_MinFeretDiameter Smoking 0.346 0 0.027
Geometry Median_Identifyhemasub2_AreaShape_MinorAxisLength Smoking 0.342 0 0.027
Geometry Median_Identifyhemasub2_AreaShape_Perimeter Smoking 0.247 0.006 0.085
Geometry Median_Identifyhemasub2_AreaShape_Zernike_4_4 Smoking −0.242 0.002 0.059
Geometry Median_Identifyhemasub2_AreaShape_Zernike_5_1 Smoking −0.256 0.003 0.073
Texture Median_Identifyhemasub2_Granularity_13_ImageAfterMath Smoking −0.311 0.001 0.049
Texture Median_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_01 Smoking 0.319 0.001 0.049
Texture Median_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_02 Smoking 0.274 0.005 0.081
Texture Median_Identifyhemasub2_Texture_Correlation_ImageAfterMath_3_03 Smoking 0.394 0 0.01
Texture StDev_Identifyeosinprimarycytoplasm_Texture_SumAverage_maskosingray_3_00 Smoking 0.272 0.003 0.073
Texture StDev_Identifyeosinprimarycytoplasm_Texture_SumAverage_maskosingray_3_01 Smoking 0.273 0.003 0.073
Texture StDev_Identifyeosinprimarycytoplasm_Texture_SumAverage_maskosingray_3_02 Smoking 0.270 0.004 0.074
Texture StDev_Identifyeosinprimarycytoplasm_Texture_SumAverage_maskosingray_3_03 Smoking 0.275 0.003 0.073
Geometry StDev_identifyhemaprimarynuclei_Location_Center_Y Smoking −0.245 0.007 0.093
Geometry StDev_Identifyhemasub2_AreaShape_Zernike_8_4 Smoking −0.280 0.001 0.045
Geometry StDev_Identifyhemasub2_AreaShape_Zernike_8_8 Smoking −0.236 0.007 0.094
Texture StDev_Identifyhemasub2_Texture_SumVariance_ImageAfterMath_3_01 Smoking 0.266 0.007 0.096
Texture StDev_Identifyhemasub2_Texture_SumVariance_ImageAfterMath_3_02 Smoking 0.283 0.005 0.079
Texture StDev_Identifyhemasub2_Texture_SumVariance_ImageAfterMath_3_03 Smoking 0.283 0.006 0.084
Geometry StDev_identifytissueregion_Location_Center_Y Smoking −0.289 0.002 0.059
Texture Texture_Correlation_ImageAfterMath_3_01 Smoking 0.252 0.004 0.078
Texture Texture_Correlation_ImageAfterMath_3_03 Smoking 0.329 0 0.027
Texture Texture_Correlation_maskosingray_3_03 Smoking 0.237 0.004 0.074
Texture Texture_Entropy_ImageAfterMath_3_01 Smoking 0.220 0.007 0.093
Texture Texture_Entropy_ImageAfterMath_3_03 Smoking 0.233 0.004 0.074